Wrinkle relaxers, also called neuromodulators, are injectable treatments that temporarily reduce the appearance of lines and wrinkles by relaxing the underlying facial muscles. They target dynamic wrinkles, the lines that form from repeated expressions like squinting, frowning, and raising your eyebrows. At Cienega Medical, we offer four FDA-approved wrinkle relaxers: Botox, Dysport, Xeomin, and Letybo. Each uses botulinum toxin type A to block nerve signals that trigger muscle contraction, but they differ in formulation, onset speed, and how they spread beneath the skin.
Choosing the right wrinkle relaxer depends on the treatment area, your skin, and how your body has responded to previous treatments. Some patients prefer Dysport for broader areas like the forehead, while others choose Xeomin for its purified “naked” formulation. Letybo, the newest FDA-approved option, offers fast onset that many patients notice within 2 to 3 days. Your provider will recommend the best fit during a complimentary consultation at any of our three Los Angeles locations in West Hollywood, Calabasas, and Santa Monica.
All four are botulinum toxin type A products that relax muscles to smooth wrinkles. The key differences are in their formulation. Botox and Dysport contain complexing proteins, while Xeomin is a "naked" neurotoxin with no additives. Letybo is the newest option, offering a purified formulation. Dysport tends to spread more, making it popular for larger areas like the forehead. Your provider can explain which may work best for your goals.
Your provider will consider the treatment area, your aesthetic goals, and your history with injectables. First-time patients often start with Botox or Dysport. Patients who develop resistance to one product sometimes switch to Xeomin. Letybo is a newer alternative that some patients prefer. There is no single "best" product; it depends on your individual response.
Most wrinkle relaxers last 3-4 months, though this varies by individual, treatment area, and product used. Some patients find Dysport kicks in faster (2-3 days vs 5-7 for Botox) but may wear off slightly sooner. Regular maintenance treatments can help results last longer over time.
Common treatment areas include forehead lines, frown lines (the "11s" between the brows), and crow's feet. Advanced applications include brow lifts, bunny lines, lip flip, chin dimpling, jawline slimming (masseter), and neck bands. Your provider will assess which areas would benefit most.
Most patients describe a brief pinching sensation. The needles used are very fine, and treatments take only 15-20 minutes. No numbing is typically needed, though we can apply ice or topical numbing if you prefer.
No downtime is required. You can return to normal activities immediately. We recommend avoiding strenuous exercise for 24 hours and not lying flat for 4 hours after treatment. Minor redness or swelling at injection sites typically resolves within an hour.
Yes. Many patients try different options over time. Since all four products work through the same mechanism, switching is safe and straightforward. Your provider can help you evaluate whether a different product might better suit your needs.
Dysport and Letybo often show results in 2-3 days. Botox and Xeomin typically take 5-7 days for full effect, with peak results at about 2 weeks. Your provider will schedule a follow-up if needed to assess results and make any touch-up adjustments.
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