What is Thymosin Beta-4 (TB-4)?

Thymosin Beta-4 is a naturally occurring 43-amino acid peptide found in many cells throughout the body. It is one of the more abundant intracellular proteins in mammalian cells and has been a subject of laboratory research, particularly regarding its role in cell structure and movement through its interaction with actin.

What is the difference between TB-4 and TB-500?

TB-4 (Thymosin Beta-4) refers to the full naturally occurring 43-amino acid peptide. TB-500 is the name commonly used for a synthetic peptide fragment that corresponds to a portion of the TB-4 sequence. The two terms are often discussed together in peptide literature but are not identical molecules.

Is Thymosin Beta-4 (TB-500) FDA-approved?

No. Neither Thymosin Beta-4 nor the synthetic fragment TB-500 is approved by the U.S. Food and Drug Administration for human use. The FDA has not evaluated these peptides for safety or effectiveness, and they remain research compounds rather than approved medications.

Cienega Medical · Since 2010

Thymosin Beta 4 Peptide Therapy

Medical Director: Dr. Neal Kumar, MD, MBA, FAAD

Understanding Thymosin Beta-4 (TB-4 / TB-500)

An educational overview of the peptide Thymosin Beta-4, including its biology and regulatory status in the United States.

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Important Information

Thymosin Beta-4 (TB-500) is not FDA-approved and is not offered at Cienega Medical. This page is for general education only and is not medical advice.

What Is Thymosin Beta-4?

Thymosin Beta-4 (TB-4) is a naturally occurring 43-amino acid peptide found in many cells and tissues throughout the body, and it is among the more abundant intracellular proteins in mammalian cells. A synthetic fragment marketed under the name TB-500 corresponds to a portion of the TB-4 sequence. In the body, Thymosin Beta-4 is studied in the context of cell biology, including its interaction with actin, a structural protein involved in cell movement. Thymosin Beta-4 and TB-500 are not approved by the U.S. Food and Drug Administration (FDA) for the treatment of any condition, and the FDA has not evaluated them for safety or effectiveness in humans.

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What is Thymosin Beta-4 (TB-4)?
Thymosin Beta-4 is a naturally occurring 43-amino acid peptide found in many cells throughout the body. It is one of the more abundant intracellular proteins in mammalian cells and has been a subject of laboratory research, particularly regarding its role in cell structure and movement through its interaction with actin.
What is the difference between TB-4 and TB-500?
TB-4 (Thymosin Beta-4) refers to the full naturally occurring 43-amino acid peptide. TB-500 is the name commonly used for a synthetic peptide fragment that corresponds to a portion of the TB-4 sequence. The two terms are often discussed together in peptide literature but are not identical molecules.
Is Thymosin Beta-4 (TB-500) FDA-approved?
No. Neither Thymosin Beta-4 nor the synthetic fragment TB-500 is approved by the U.S. Food and Drug Administration for human use. The FDA has not evaluated these peptides for safety or effectiveness, and they remain research compounds rather than approved medications.