2015, Mice (Cell Metabolism)
2015 study on PubMed
MOTS-c: $99
Your telehealth visit is free. If you buy, we add a $49 medication review for your prescription.
Nothing to pay to book. California residents only.
Our nurse calls you at the time you pick, wherever you are in California. Pick it up at Calabasas, Santa Monica or West Hollywood, or have it shipped home.
Your prescription is filled by a licensed U.S. 503A pharmacy.
Nothing is dispensed without a prescription from our medical team.
Every order adds one $49 medication review. Free delivery anywhere in California, or pick it up at any clinic.
MOTS-c is prescribed after a consultation. People ask about it mainly for metabolism and energy rather than a specific condition.
Adults focused on metabolic health and steady energy
Active people supporting endurance and recovery
Anyone taking a healthy-aging approach with a provider
Book a free consultation with our medical team to talk it through.
MOTS-c is unusual: it is a sixteen-amino-acid peptide encoded not in the cell nucleus but in mitochondrial DNA, the DNA inside the structures that make cellular energy. It is often described as an exercise-mimetic because research links it to how the body uses fuel. Interest centers on metabolism, energy, and healthy aging. It is a research peptide, prescription-only.
Metabolic flexibility and how the body burns fuel
Insulin sensitivity and glucose handling
Fat oxidation and energy production
Athletic performance and healthy aging
MOTS-c was discovered in Los Angeles, at USC, in 2015. Most of what is known so far comes from cell and animal studies.
MOTS-c is not FDA-approved for any use. These studies don’t show that it treats any condition in people, and safety data in people are limited. Your free consultation with a nurse practitioner is the place to talk through what is and isn’t known.
Most peptides are not FDA-approved for the uses discussed publicly, and are prescribed at the discretion of a licensed provider after an individual evaluation. A peptide is not appropriate for everyone, and individual results vary.
Peptide therapy at Cienega Medical is available by prescription only. You start with a consultation with one of our nurse practitioners, who reviews your health history, your goals, and whether a peptide is appropriate for you. If it is, they write the prescription and we prepare it for your visit. If it is not, they will tell you that too.
MOTS-c is a short peptide, sixteen amino acids long, that is unusual in where it comes from: it is encoded not in the DNA of the cell nucleus but in the separate DNA carried inside mitochondria, the structures that produce energy within cells. It was identified relatively recently, in 2015, and researchers have studied it mainly in relation to metabolism, insulin sensitivity, and how cells respond to exercise. Most of the research so far has been in cell and animal models, and it is an active area of study. MOTS-c is a research peptide, available at Cienega by prescription only.
MOTS-c is a peptide of sixteen amino acids encoded in mitochondrial DNA rather than in the cell nucleus. Researchers have studied it mainly in relation to metabolism and insulin sensitivity, sometimes calling it an exercise mimetic because of how it behaves in laboratory models. The human research is very little so far, mostly cell and animal models rather than large human trials, which your nurse practitioner can put in context at your free consultation.
No. MOTS-c is not approved by the FDA for any use.
MOTS-c is not right for everyone. Your nurse practitioner reviews your health history, current medications and any existing conditions before prescribing and will tell you if it is not a fit. Bring your current medication list to your free consultation.
Bottle prices are listed on this page. Every order includes one medication review fee, which covers the review and managing your prescriptions, and is charged once even when prescriptions go out as separate orders the same day. The consultation itself is free.
Pick a time for a free telehealth visit with a nurse practitioner, by phone or video. Before your visit, you fill out a short health form. They go through your health history, your current medications and what you are trying to achieve, then tell you whether this is a sensible fit. Not everyone is, and if you are, they write the prescription and you pay for your bottles plus one medication review fee.
Your prescription is filled by a licensed U.S. 503A compounding pharmacy.
That depends on what your provider prescribes, so it is not something we can put a number on here. Your nurse practitioner tells you at your review roughly how long a bottle should last for you and when it would make sense to order again. You can order as many bottles as your nurse prescribes while you’re on the call, and when you need more, book another call online or call us. Each call where you order adds one $49 medication review. Nothing renews on its own. If you’d like bottles sent on a regular schedule, ask your nurse: it’s worked out case by case, since everyone’s prescription is different.
Both. Collect at West Hollywood, Santa Monica or Calabasas, where we pack it for you and show you how to inject it, all covered by the medication review fee. Or we ship it to your home anywhere in California, at no extra charge.
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